Kartik Chandran

Kartik Chandran

@ChandranLab

Followers1.4K
Following369

Virologist researching #Ebola, #hantavirus, other emerging viruses at Albert Einstein College of Medicine in NYC. Contact: kartik.chandran@einstein.yu.edu

New York City
Joined on May 13, 2011
Statistics

We looked inside some of the tweets by @ChandranLab and here's what we found interesting.

Inside 100 Tweets

Time between tweets:
3 days
Average replies
67
Average retweets
511
Average likes
1731
Tweets with photos
21 / 100
Tweets with videos
0 / 100
Tweets with links
0 / 100
Today’s pick is a paper from Howard Hang, @ChandranLab, and Tao Peng from our March 2019 issue in which they showed palmitoylated IFITM3 localizes to endocytic vesicles that fuse with incoming viruses and enhance their traffic to lysosomes. https://t.co/q1Sd3pSd4g https://t.co/QQk7Ug6mGa

Today’s pick is a paper from Howard Hang, @ChandranLab, and Tao Peng from our March 2019 issue in which they showed palmitoylated IFITM3 localizes to endocytic vesicles that fuse with incoming viruses and enhance their traffic to lysosomes. https://t.co/q1Sd3pSd4g https://t.co/QQk7Ug6mGa

Quoted @ChandranLab

Our new preprint on recombinant VSV expressing SARS-CoV-2 spike protein is out. Highly infectious, suitable for entry studies, inhibitor and neut antibody screening, more, esp in tandem w new authentic SARS2 microneut assay. Amazing team effort! https://t.co/SgO8NAlWJ0. #Covid_19 https://t.co/jrVYGbSPh6

Our new preprint on recombinant VSV expressing SARS-CoV-2 spike protein is out. Highly infectious, suitable for entry studies, inhibitor and neut antibody screening, more, esp in tandem w new authentic SARS2 microneut assay. Amazing team effort! https://t.co/SgO8NAlWJ0. #Covid_19 https://t.co/jrVYGbSPh6

Nice work, @ChandranLab! Except the last time I saw you, you had three dimensions and actual feet... https://t.co/2KZWZlOky2

Thank you to all of our collaborators at @EinsteinMed, @MontefioreNYC, USAMRIID, @WestPoint_USMA, and to @Jangra_RohitK, @EugeDieterle , @HaslwanterD, Andrew Herbert for leading this work. Satisfying parallels with recent preprint from @vsv512 and his colleagues.

Our new preprint on recombinant VSV expressing SARS-CoV-2 spike protein is out. Highly infectious, suitable for entry studies, inhibitor and neut antibody screening, more, esp in tandem w new authentic SARS2 microneut assay. Amazing team effort! https://t.co/SgO8NAlWJ0. #Covid_19 https://t.co/jrVYGbSPh6
2

Our new preprint on recombinant VSV expressing SARS-CoV-2 spike protein is out. Highly infectious, suitable for entry studies, inhibitor and neut antibody screening, more, esp in tandem w new authentic SARS2 microneut assay. Amazing team effort! https://t.co/SgO8NAlWJ0. #Covid_19 https://t.co/jrVYGbSPh6

In this time of outbreak, important work made by devoted researchers ⁦⁦⁩to elicit the answers and tools to elaborate and offer treatment for all! ⁦@ChandranLab⁩ ⁦@EinsteinMed#COVIDー19 #Vaccine #ScienceMatters https://t.co/dCBadiqoSc

Congrats to the Einstein scientists and Montefiore clinicians for creating an antibody test for coronavirus. We are excited for the grad students from the @ChandranLab, Lai and Almo Labs to be part of this important development https://t.co/FwXCvXK9Df #7daysonthefrontline

@ChandranLab Looks great! Nice correlation of the neut assays and ELISA

Just been informed that USAMRIID doesn't have a Twitter handle. Oops. 😅 Here is the real deal: https://t.co/tNnq3ek6FH

Thank you to @ChandranLab COVID-19 team of 8 who are doing this work: Rob Bortz, Euge Dieterle, @MaxFels , Catalina Florez, @_nyudonna_ , @Jangra_RohitK, Ethan Laudermilch, @ArielWirch. Thanks also to our Lab Ops team and other KCLab peeps who are supporting these efforts.

Neut. potential of these sera also correlates with their overall level of SARS2 spike-specific IgG antibodies, as measured by  ELISA. We set this up using a stabilized spike  construct generously provided by our collaborator @McLellan_Lab. Looks beautiful (see EM), works great! https://t.co/10Z0D3i0JE
2

Neut. potential of these sera also correlates with their overall level of SARS2 spike-specific IgG antibodies, as measured by ELISA. We set this up using a stabilized spike construct generously provided by our collaborator @McLellan_Lab. Looks beautiful (see EM), works great! https://t.co/10Z0D3i0JE

Sharing new data with VSV-SARS2 spike surrogate virus made by @Jangra_RohitK in my lab. 'Real' SARS2 and our VSV are similarly neutralized by antibodies in different convalescent sera. The SARS2 assay is a novel 'microneut' format developed by my collaborator John Dye @USAMRIID. https://t.co/wxYeyjsxvh

Sharing new data with VSV-SARS2 spike surrogate virus made by @Jangra_RohitK in my lab. 'Real' SARS2 and our VSV are similarly neutralized by antibodies in different convalescent sera. The SARS2 assay is a novel 'microneut' format developed by my collaborator John Dye @USAMRIID. https://t.co/wxYeyjsxvh

Currently in progress! No results yet.

Check out our new paper on the role of dopamine in real-time effort-reward integration: https://t.co/gKaIt81oYf

I'm assuming folks are trying to culture virus from positive swab samples of individuals that have already convalesced from COVID-19 and have returned to their homes. Is there any data on this yet? Thanks!

Reporting on the collection of COVID19 convalescent sera in New Rochelle by Young Israel congregation for therapy. This is a remarkable effort that has been organized very rapidly. My colleague Dr. Liise-anne Pirofski is quoted. https://t.co/1YqzwEM9Jd

in case you didn't know: NYC Health + Hospitals runs all of the city's public facilities, including Elmhurst, Bellevue and Jacobi — among the hospitals hardest hit right now Staff at Jacobi held a protest begging for equipment this morning: https://t.co/giy176r61o

Wading into anti-CoV spike antibodies: I am in full support of this approach for #SARS2 vaccines. Neutralizing spike antibody is the main correlate for protection from lethal SARS-CoV and MERS-CoV disease. I think neutralizing #SARS2 ab are key to protection

The funniest part about preparing to do a live CNN interview from my home office was trying to convince my teenage sons not to video-bomb the segment while yelling “FLATTEN THE CURVE, BITCHES!”

Never have I ever... ...taken care of so many -very- sick colleagues and friends. I can only hope I won't end up like them. But I know there's a good chance I will. #COVID19 is gutting the front line.

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